T Miyano, AD Irvine, RJ Tanaka (2021). A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis. Allergy.
Eczema Pathogenesis
J Nousbeck, MA McAleer, G Hurault, E Kenny, K Harte, S Kezic, RJ Tanaka, AD Irvine (2020). miRNA analysis of Childhood Atopic Dermatitis reveals a role for miR-451a. British Journal of Dermatology.
Eczema Pathogenesis
K Eyerich, SJ Brown, BEP White, RJ Tanaka, R Bissonette, S Dhar, T Bieber, D Hijnen, E Guttman-Yassky, AD Irvine, JP Thyssen, C Vestergaard, T Werfel, A Wollenberg, AS Paller, NJ Reynolds (2019). Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council. Journal of Allergy and Clinical Immunology.
Eczema Pathogenesis
G Tanaka, E Domínguez-Hüttinger, P Christodoulides, K Aihara, RJ Tanaka (2018). Bifurcation analysis of a mathematical model of atopic dermatitis to determine patient-specific effects of treatments on dynamic phenotypes. Journal of Theoretical Biology.
Eczema Pathogenesis
AG Giannari, MDA van Logtestijn, P Christodoulides, K Konishi, RJ Tanaka (2018). Model Predictive Control for Designing Proactive Therapy of Atopic Dermatitis. 2018 European Control Conference (ECC).
Eczema Pathogenesis
E Domínguez-Hüttinger, P Christodoulides, K Miyauchi, AD Irvine, M Okada-Hatakeyama, M Kubo, RJ Tanaka (2017). Mathematical modeling of atopic dermatitis reveals “double-switch” mechanisms underlying 4 common disease phenotypes. Journal of Allergy and Clinical Immunology.
Eczema Pathogenesis
P Christodoulides, Y Hirata, E Domínguez-Hüttinger, SG Danby, MJ Cork, HC Williams, K Aihara, RJ Tanaka (2017). Computational design of treatment strategies for proactive therapy on atopic dermatitis using optimal control theory. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences.
Eczema Pathogenesis
MDA van Logtestijn, PJ Caspers, S Kezic, DR Hoffman, DW Koenig, M Ono, GN Stamatas, RJ Tanaka (2016). Water resistance profile as a marker of skin barrier damage in atopic dermatitis patients. Journal of Dermatological Science.
Eczema Pathogenesis
RJ Tanaka, M Ono (2013). Skin disease modeling from a mathematical perspective. Journal of Investigative Dermatology.
Eczema Pathogenesis
E Domínguez-Hüttinger, M Ono, M Barahona, RJ Tanaka (2013). Risk factor-dependent dynamics of atopic dermatitis: Modelling multi-scale regulation of epithelium homeostasis. Interface Focus.
Eczema Pathogenesis
RJ Tanaka, M Ono, HA Harrington (2011). Skin barrier Homeostasis in atopic dermatitis: Feedback regulation of kallikrein activity. PLoS ONE.